Materia Medica
Antipyrine
Phenazone - A Coal-tar Derivative
Antipyrine is one of the drugs that induce leucocy- tosis, similar to ergotin, salicylates, and tuberculin. Acts especially on the vaso-motor centers, causing dilation of capillaries of skin and consequent circumscribed patches of hyperaemia and swelling. In large doses causes pro- fuse perspiration, dizziness, cyanosis, and somnolence, albumen and blood in urine.
Mind
Fear of becoming insane; nervous anxiety; hallucinations of sight and hearing.
Head
Throbbing headache; sensation of constric- tion. Flashes of heat. Headache under ears with ear- iche.
Eyes
I'uffiness of lids. Conjunctiva red and ceode- matous, with lachrymation. Red spots. [Apis.]
Ears
Pains and buzzing. Tinnitus.
Face
CEdema and puffness. Red and swollen.
Mouth
Swelling of lips. Burning of mouth and gums. Ulceration of lips and tongue; vesicles and bulla. Small lump in cheek. Tongue swollen. Bloody saliva. Toothache along lower jaw.
Throat
P'ain on swallowing. Expectoration of fetid pus. Abscess, white false membrane. Sensation of burning.
Stomach
Nausea and vomiting; burning and pain. Urine. -- Diminished. Penis black.
Female
Itching and burning in vagina. Menses suppressed. Watery leucorrhcea.
Respiratory
Fluent coryza. Nasal mucous mem- brane swollen. Dull pains in frontal sinus. Aphonia. Oppression and dyspnoea. Cheyne-Stokes respiration.
Heart
Faintness, with sensation of stoppage of Throbbing throughout the body. Rapid, weak, irregular pulse. Nerves. -—- Epileptiform seizures. Contractures. Trem- bling ani cramps. Crawling and nvmbness. General prostration.
Skin
Erythema, eczema, pemphigus. Intense pru- ritus. Urticaria, appearing and disappearing suddenly, with internal coldness. Angioneurotic-cedema. Dark blotches on skin of penis, sometimes with cedema.
Dose
Second decimal potency.